CompletedNot Applicable

Treatment of Functional Movement Disorders With Psychotherapy

United States9 participantsStarted 2012-12-11

Plain-language summary

Background: \- Functional movement disorder (FMD) is a form of conversion disorder (CD). CD is a disorder in which a person has neurological symptoms that do not have a neurological cause. These symptoms can include pain, weakness, dizziness, and fatigue. Some thoughts on CD suggest that it may come from feelings of anxiety that are converted into physical symptoms. Treatment for FMD usually involves stress reduction, family help, and regular doctor s appointments. Therapy interventions, however, have not been well studied. Researchers want to see if people with FMD get better with psychotherapy. They will study two different types of psychotherapy: group therapy and a self-help manual. Objectives: \- To test two different types of therapy treatments for FMD. Eligibility: \- Individuals at least 18 years of age who have been diagnosed with FMD by a neurologist. Design: * Participants will be screened with a physical exam and medical history. They will also have a psychological exam, and answer questions about their mood and symptoms. * Participants will be separated into three groups. One group will have group therapy. Another will use a self-help workbook designed for people with FMD, and have individual therapy sessions. A third group will just have standard care. During the study, participants will continue to see their regular doctor. * Group therapy participants will meet once a week for 6 months at the National Institutes of Health clinical center. There will be 8 to 10 people per group. Sessions will last 75 minutes. These sessions will work on methods for treating FMD. * Self-help workbook participants will have six individual therapy sessions over 3 to 4 months. They will use the workbooks to learn about and practice methods for treating FMD. * All participants will be evaluated at 3, 6, and 12 months during the study. * At the end of the study, participants will have a final follow-up session with exams and questions similar to the screening exam. They will return to the care of their regular doctor.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

* INCLUSION CRITERIA: * Must have participated in Protocol 07-N-0190 ( Neurobiological studies of psychogenic movement disorder and non-epileptic seizure ) * Diagnosis of clinically definite FMD utilizing Fahn and Williams criteria. The diagnosis must be made by a neurologist * Patients who have active movement symptoms at baseline and score at least 20 percent less than the maximum score on the Neuro-QOL Item Bank * Able to give informed consent * All participants should be English-speaking * Age 18 or older * Willingness to come without reimbursement to treatment visits for up to 6 months * Willingness to remain on the same medications for the entire duration of the study EXCLUSION CRITERIA: * Have significant neurological disorders (primary or comorbid) such as neurodegenerative disorders, stroke, movement disorders or epilepsy * Patients with psychotic disorders or bipolar disorder * Patients with history of alcohol and substance use disorders within the last year, as defined by the DSM-IV-TR (nicotine and caffeine use is not criterion for exclusion) * Current suicidal/homicidal ideation * Disease severity requiring inpatient treatment. Chronic pain requiring treatment with narcotic medication ADDITIONAL EXCLUSIONAL CRITERIA FOR MRI: * Patients with movement symptoms at rest that may substantially inhibit resolution, comfort, or safety of MRI * Previous history of or MRI findings consistent with brain tumors, strokes, trauma or arterial venous malformations * History …

What they're measuring

Ability to participate in social roles and activities (Neuro-QOL Item Bank)

Timeframe: 6 months

Trial details

NCT IDNCT01778517

SponsorNational Institute of Neurological Disorders and Stroke (NINDS)

Sponsor typeNIH

Study typeINTERVENTIONAL

Primary completion2015-07-23