CompletedNot Applicable

Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy

United States73 participantsStarted 2013-01

Plain-language summary

This study will evaluate a type of Magnetic Resonance Imaging (MRI) sequence called arterial spin labeling (ASL). The investigators hope that ASL can better localize areas of the brain (lesions) that cause epilepsy. This type of MRI does not require contrast, does not use any radiation, and adds on 4 minutes to the routine MRI that is done for patients with epilepsy. The study hypothesis is that in patients with refractory epilepsy, Arterial Spin Labeling (ASL) MRI will show areas of abnormality in the brain to the same degree as single-photon emission computerized tomography (SPECT) and positron emission tomography (PET) studies.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Medically refractory partial epilepsy. * Over the age of 18 years. * Scheduled to have routine epilepsy-protocol MRI after initial evaluation in neurology clinic at Mayo Clinic, Rochester. * Anticipated to undergo epilepsy monitoring unit (EMU) monitoring. Exclusion Criteria: * Patients with a generalized epilepsy. * Under the age of 18 years. * Unable to undergo MRI imaging of the brain.

What they're measuring

Intensity of the MRI Signal in the Left Temporal Precentral Zone

Timeframe: Approximately in the middle of the MRI procedure

Trial details

NCT IDNCT01772654

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-11

Results submitted2015-02-17

View on ClinicalTrials.gov More Focal Epilepsy trials