CompletedNot Applicable

Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee

United States91 participantsStarted 2013-01-18

Plain-language summary

The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for stable forms of juvenile osteochondritis dissecans (JOCD) lesions. This study also aims to better define the natural history of this condition in its most commonly identified pathological state (as a stable lesion) following surgical intervention by determining the rate of radiographic healing and any need for secondary surgery.

Who can participate

Age range8 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of JOCD, * Lesion located on the lateral aspect of the medial femoral condyle, * Lesion considered stable based on MRI, * Patient deemed skeletally immature based on MRI, * Completed a course of conservative therapy. Exclusion Criteria: * Significant concomitant knee pathology (AVN, fracture, inflammatory arthritis, ACL tear, discoid/meniscal tear, etc.) * Lesion healed sufficiently and surgery is not recommended, * Prior surgery on the affected knee, * Diagnosis of metabolic bone disorder (e.g. osteogenesis imperfecta), * Diagnosis of sickle cell disease, * History of prolonged corticosteroid or chemotherapy treatment,

What they're measuring

Physical functioning measured by the Pedi-IKDC (International Knee Documentation Committee) total score

Timeframe: One year post-surgery

Trial details

NCT IDNCT01754298

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07-29

View on ClinicalTrials.gov More Juvenile Osteochondritis Dissecans trials