CompletedNot Applicable

Severe Asthma Research Program - Wake Forest University

United States87 participantsStarted 2012-12

Plain-language summary

The mission of SARP is to improve the understanding of severe asthma through the integrated study of the effect of genetics on the clinical and biological features of asthma and to investigate how these change over time. The ultimate goal of these efforts is to promote better treatments for severe asthma.

Who can participate

Age range6 Years

SexALL

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Inclusion criteria

✓. Physician diagnosis of asthma,
✓. Age 6 years and older
✓. Evidence of historical reversibility, including either:

Exclusion criteria

✕. No primary medical caregiver
✕. Pregnancy (only if undergoing methacholine challenge or bronchoscopy)
✕. Current smoking
✕. Smoking history \> 10 pack years if ≥ 30 years of age or smoking history \>5 pack years if \< 30 years of age (Note: If a subject has a smoking history, no smoking within the past year)
✕. Other chronic pulmonary disorders associated with asthma-like symptoms, including (but not limited to) cystic fibrosis, chronic obstructive pulmonary disease, chronic bronchitis, vocal cord dysfunction that is the sole cause of asthma symptoms, severe scoliosis or chest wall deformities that affect lung function, or congenital disorders of the lungs or airways
✕. History of premature birth before 35 weeks gestation
✕. Planning to relocate from the clinical center area before study completion

What they're measuring

Change in pulmonary function over time

Timeframe: 36 months

Trial details

NCT IDNCT01750411

SponsorWake Forest University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-02-18

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