CompletedPhase 2

Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis

Bangladesh60 participantsStarted 2011-10

Plain-language summary

Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil capsule orally for 12 weeks to examine its effectiveness in reducing body arsenic load and clinical symptoms. Similar treatment with similar number of arsenic exposed controls and healthy volunteers will be included for comparison.

Who can participate

Age range20 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria (Patients): * history of taking arsenic contaminated water (\>50 ppb) for more than 6 months * patients having mild to moderate arsenical keratosis present on palm of the hand * patients those voluntarily agree to participate Inclusion Criteria (Arsenic exposed controls): * family member of the patient * drinking arsenic contaminated water from the same source as patient * those voluntarily agree to participate * no sign/symptom of palmer keratosis Inclusion Criteria (Healthy volunteers): * drinking arsenic safe water (\<50 ppb) * those voluntarily agree to participate Exclusion Criteria: * pregnancy * lactating mother * patient receiving treatment of arsenicosis * any other chronic disease like tuberculosis, diabetes mellitus, bronchial asthma

What they're measuring

Change in the clinical symptom of keratosis in palm

Timeframe: 0 week (baseline) to 12 weeks (end)

Trial details

NCT IDNCT01748669

SponsorBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-07

View on ClinicalTrials.gov More Chronic Arsenic Poisoning trials