CompletedNot Applicable

The Realtime Detection for Individual Variation of Analgesic ：A Comparison of Sufentanil vs Fentanyl

China120 participantsStarted 2012-06

Plain-language summary

Purpose: This study aimed to find a quick and timely way to investigate the individual variation of efficacy of opioid analgesic in Chinese patients undergoing elective surgeries. Methods: 120 female patients receiving elective surgery under general anesthesia were recruited into this study. At the time of routine intravenous anesthetic induction we observe the efficacy of opioid analgesic including analgesic effect, effects on Narco-trend index, sedative effect, effects on respiratory system, and aslo effects on cardiovascular system.

Who can participate

Age range20 Years – 65 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 20-65 years * Anesthesiologists (ASA) physical status I or II; * Within ±20% of ideal body weight; * Agreed to participate the research Exclusion Criteria: * History of chronic pain; * Psychiatric diseases; * Diabetes mellitus; * Severe cardiovascular diseases; * Kidney or liver diseases; * Alcohol or drug abuse (according to the criteria of DSM-IV); * Pregnancy or at lactation period; * Disagree to participate to the research

What they're measuring

Mean Pressure Pain Threshold

Timeframe: 10 minutes after the procedure

Mean Value of Narco-trend Index

Timeframe: 10 minutes after the procedure

Trial details

NCT IDNCT01748071

SponsorHuazhong University of Science and Technology

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-12

Results submitted2013-05-30

View on ClinicalTrials.gov More Surgery trials