Omega-3 and Blueberry Supplementation in Age-Related Cognitive Decline

Inclusion Criteria: * men and women aged 62 to 80 years and older * age-associated decline operationalized as Clinical Dementia Rating = 0, Auditory Verbal Learning Test cumulative acquisition score between 1.0 standard deviation below and 1.0 standard deviation above the age-corrected mean or Montreal Cognitive Assessment score greater than 25, and Geriatric Depression Scale score less than 16 * ability to comprehend and comply with the research protocol * provision of written informed consent. Exclusion Criteria: * established dementia or neurological disorder including but not limited to probable Alzheimer's Disease, Parkinson's Disease, Frontotemporal dementia, multi-infarct dementia, and leukoencephalopathy * current or past severe psychiatric disorder such as psychosis or major mood disorder requiring hospitalization and/or causing a change in level of occupational or social functioning * current or past alcohol or drug abuse disorder causing physiological dependence or change in functional capability (nicotine dependence is permitted) * diagnosis of diabetes or other metabolic disorder or kidney or liver disease * use of medication that might affect outcome measures or interact with omega 3 fatty acid supplements such as benzodiazepines, aspirin, and serotonin reuptake inhibitors * hematological coagulation disorder * allergy to shellfish or seafood; 8) current supplementation with fish oil or consumption of fish more than once per week.