CompletedNot Applicable

Postoperative Vomiting in Children: Comparison Tri - Versus bi -Prophylaxis

France322 participantsStarted 2010-12

Plain-language summary

The purpose of this study is to evaluate the benefit of addition of droperidol to prophylaxis with ondansetron and dexamethasone in children with high risk of postoperative vomiting (POV). In adults some authors showed that the effectiveness of prophylaxis is correlated to the number of molecules or specific procedures used.

Who can participate

Age range3 Years – 17 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children scheduled for surgery and with high risk of postoperative vomiting, i.e. with VPOP score up to 4 * Between 3 to 18 years * Informed consent signed or the owner (s) of parental * Children receiving a social security system Exclusion Criteria: * Ambulatory surgery * Preoperative corticosteroids * Postoperative sedation * Allergy known to droperidol, ondansetron or dexamethasone * Known hypokaliemia * Known hypomagnesemia * Bradycardia (\<55 bpm) * Congenital long QT syndrome * Treatment that induce prolonged QT * Pheochromocytoma * Severe depressive syndrome

What they're measuring

Postoperative vomiting

Timeframe: 24 hours

Trial details

NCT IDNCT01739985

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-07

View on ClinicalTrials.gov More Postoperative Vomiting trials