A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare

Note for Age Eligibility: * Cardiology patients 18 Years to 90 Years OR * Primary Care Patients 40 Years to 65 Years (Adult, Senior) Inclusion Criteria: Primary Care * Generally healthy (as defined by the primary care provider) adult patients at Brigham and Women's Hospital ages 40-65. All patients must be fluent in English. Cardiology * Patients in the Partners Healthcare System who are 18 years or older with a diagnosis of hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM) and a family history of HCM or DCM who previously had or who are candidates for targeted HCM or DCM genetic testing through routine clinical practice within Partners. All patients must be fluent in English. Exclusion Criteria: Primary Care * Patients who do not meet the above criteria. Patients with cardiac disease or a progressive debilitating illness. Patients who are pregnant or patients whose spouses/significant others are pregnant. Patients with untreated clinical anxiety or depression (as measured by a Hospital Anxiety and Depression Scale (HADS) score \> 11 administered at the baseline study visit.) Cardiology * Patients who do not meet the above criteria. Patients with a progressive debilitating illness. Patients who are pregnant or patients whose spouses/significant others are pregnant. Patients with untreated clinical anxiety or depression (as measured by a Hospital Anxiety and Depression Scale (HADS) score \> 11 administered at the baseline study visit.) Extension Pha…