Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy

Inclusion Criteria: * Term or near-term newborn (\> = 36 weeks gestational age) * Moderate to severe encephalopathy * undergoing moderate controlled hypothermia started within 6 hours after delivery : rectal or esophageal temperature maintained at 33.5 ° C + / - 0.5 ° C before H6 * Beneficiary of social security plan * Informed consent parental authority Exclusion Criteria: * Impossibility of getting controlled hypothermia before H6 * Infant older than 12 hours of age * Chromosomal or significant congenital abnormality * Predictable surgery in the first 3 days of life * Uncontrolled collapse * Haemorrhagic syndrome unchecked * Head trauma with or without skull fracture