CompletedNot Applicable

Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS Meningitis

France949 participantsStarted 2012-11-12

Plain-language summary

The main objective of this study : Demonstrate that GBS (group B streptococci) "ST-17" colonize and persist to 60 days twice in the digestive tract of newborns that strains of GBS non-ST-17. Secondary objectives:Determine: * The frequency of colonization with GBS ST-17 and GBS non-ST-17 of at risk pregnant women. * The frequency of colonization of neonates by GBS ST-17 at birth. * The preferential site of colonization in the mother (rectum, vagina, breast milk). * The kinetics of colonization after birth in the newborn. * The sensitivity and specificity of different GBS detection methods (conventional phenotypic versus molecular) in the different types of samples from the mother and the newborn.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient having a positive vaginal swab for GBS at the end of pregnancy (PCR +). * Patient aged over 18 years * Patient who received information and agreeing to sign informed consent * Patient affiliated or beneficiary of an insurance Exclusion Criteria: \- Patient does not speak and does not understand French

What they're measuring

Detection of the hyper-virulent ST17 clone of Group B Strep

Timeframe: at 60 days post delivery

Trial details

NCT IDNCT01719510

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-06-03

View on ClinicalTrials.gov More Neonatal Infections Colonize With Group B Streptococci trials