TerminatedNot Applicable

Tests of Functional Magnetic Resonance Imaging Techniques

Stopped: Changes to funding

United States13 participantsStarted 2015-03-19

Plain-language summary

Background: \- Functional magnetic resonance imaging (fMRI) is used to study the brain. It takes a series of pictures that can be used to look at how the brain processes information. It is used to study problems with thinking, language, and movement, among other things. Researchers are working to develop new and better fMRI techniques. To test these techniques, they want to perform fMRI scans on healthy volunteers. Objectives: \- To test different fMRI techniques in healthy volunteers. Eligibility: \- Healthy volunteers at least 18 years of age. Design: * Participants will be screened with a physical exam and medical history. * Participants will have fMRI scans of the brain. During these scans, they will be asked to perform simple tasks. These tasks may involve language, thinking, or motor skills. The scanning sessions will last up to 2 hours. * Participants may be asked to return for additional fMRI scans over several years.

Who can participate

Age range18 Years – 110 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

* INCLUSION CRITERIA: * Healthy volunteers, new or from current NIH protocols are eligible. Healthy volunteers will be defined according the history obtained from reported medical history, medical record (reported at registration), the MRI safety questionnaire, and a clinical grade noncontrast brain MRI. * Willing to travel to the NIH for follow-up visits * Greater than 18 years old * Able to understand and sign informed consent. * Bilingual or multilingual subjects can participate in this study as long as the subjects are also fluent in English. Subjects do not need to be native or monolingual speakers of English. EXCLUSION CRITERIA: The following criteria will be used to exclude subjects from participating in this protocol: * Implanted metal clips or wires of the type which may concentrate radiofrequency fields or cause tissue damages from twisting in a Magnetic field. Examples: * Aneurysm clip, implanted neural stimulator, * Implanted cardiac pacemaker, defibrillator, or certain other implanted electrical or metallic devices, * Cochlear implant, ocular foreign body (metal shavings), * Any implanted device (pumps, infusion devices, etc.), * Shrapnel injuries, * History of metal in head or eyes or other parts of the body. * Vagus Nerve Stimulators (VNS) * Subjects with tattoos that contain metal. * Pregnant women * Over 350 lbs because of the weight limit of the MRI table * Prior surgery that may render performing the MRI to be unsafe. * Untreatable claus…

What they're measuring

evaluation of fMRI techniques

Timeframe: Study day 1, followup visit(s)

Trial details

NCT IDNCT01712633

SponsorNational Institutes of Health Clinical Center (CC)

Sponsor typeNIH

Study typeOBSERVATIONAL

Primary completion2017-11-01