TerminatedNot Applicable

Tests of Functional Magnetic Resonance Imaging Techniques

Stopped: Changes to funding

United States13 participantsStarted 2015-03-19

Plain-language summary

Background: \- Functional magnetic resonance imaging (fMRI) is used to study the brain. It takes a series of pictures that can be used to look at how the brain processes information. It is used to study problems with thinking, language, and movement, among other things. Researchers are working to develop new and better fMRI techniques. To test these techniques, they want to perform fMRI scans on healthy volunteers. Objectives: \- To test different fMRI techniques in healthy volunteers. Eligibility: \- Healthy volunteers at least 18 years of age. Design: * Participants will be screened with a physical exam and medical history. * Participants will have fMRI scans of the brain. During these scans, they will be asked to perform simple tasks. These tasks may involve language, thinking, or motor skills. The scanning sessions will last up to 2 hours. * Participants may be asked to return for additional fMRI scans over several years.

Who can participate

Age range

18 Years – 110 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

* INCLUSION CRITERIA: * Healthy volunteers, new or from current NIH protocols are eligible. Healthy volunteers will be defined according the history obtained from reported medical history, medical record (reported at registration), the MRI safety questionnaire, and a clinical grade noncontrast brain MRI. * Willing to travel to the NIH for follow-up visits * Greater than 18 years old * Able to understand and sign informed consent. * Bilingual or multilingual subjects can participate in this study as long as the subjects are also fluent in English. Subjects do not need to be native or monolingual speakers of English. EXCLUSION CRITERIA: The following criteria will be used to exclude subjects from participating in this protocol: * Implanted metal clips or wires of the type which may concentrate radiofrequency fields or cause tissue damages from twisting in a Magnetic field. Examples: * Aneurysm clip, implanted neural stimulator, * Implanted cardiac pacemaker, defibrillator, or certain other implanted electrical or metallic devices, * Cochlear implant, ocular foreign body (metal shavings), * Any implanted device (pumps, infusion devices, etc.), * Shrapnel injuries, * History of metal in head or eyes or other parts of the body. * Vagus Nerve Stimulators (VNS) * Subjects with tattoos that contain metal. * Pregnant women * Over 350 lbs because of the weight limit of the MRI table * Prior surgery that may render performing the MRI to be unsafe. * Untreatable claus…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

evaluation of fMRI techniques

Timeframe: Study day 1, followup visit(s)

Trial details

NCT IDNCT01712633

SponsorNational Institutes of Health Clinical Center (CC)

Sponsor typeNIH

Study typeOBSERVATIONAL

Primary completion2017-11-01

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