WithdrawnNot Applicable

The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients

Stopped: Difficulty in purchasing reagents and receiving consent from the subject

South Korea0Started 2012-08

Plain-language summary

Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of hydronephrosis in pediatric ureteropelvic junction obstruction (UPJO) patients. We are trying to analyze whether it is related with the grade of renal injury in UPJO patients.

Who can participate

Age range3 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. 0-3 year old patients with SFU grade 2 or more hydronephrosis without ureteral dilatation
✓. needs pyeloplasty due to differential renal function (DRF)\<40%, decreased DRF by more than 5%, development of urinary tract infection, development of urinary stone, and development of pain related with UPJO \<Group 2\>

Exclusion criteria

✕. patients with contralateral disease affecting DRF
✕. history of previous urinary tract surgery
✕. follow up loss before diuretic renogram performed at 6-12 months from operation \<Group 2, 3\>

What they're measuring

The level of urinary NGAL and the degree of renal injury

Timeframe: 6 month after operation

Trial details

NCT IDNCT01711996

SponsorYonsei University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-08

View on ClinicalTrials.gov More Ureteropelvic Junction Obstruction trials