Is the Expression of the GLUT5 Specific Fructose Transport Protein Abnormal in Patients With Fruc… (NCT01705171) | Clinical Trial Compass
CompletedNot Applicable
Is the Expression of the GLUT5 Specific Fructose Transport Protein Abnormal in Patients With Fructose Intolerance?
Switzerland26 participantsStarted 2011-12
Plain-language summary
In this study we will investigate the expression of the fructose transport protein GLUT5 in the small intestine in patients with functional GI disoders and fructose intolerance compared to matched healthy controls.
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion Criteria:
* Patients referred to our practice for evaluation of symptoms consistent with FGID undergoing upper GI endoscopy with biopsy and fructose breath testing as part of their usual clinical evaluation. Male or female patients aged between 18 and 60 years with FGID (Irritable Bowel Syndrome (IBS), Functional Dyspepsia (FD) or Functional Bloating (FB), as defined by Rome III criteria.
* Successive patients without fructose intolerance undergoing upper GI endoscopy for other reasons without inflammatory disease
Exclusion Criteria:
* Inflammatory GI disease, coeliac's disease, other relevant systemic disorders as judged by investigator, concomitant antiinflammtory treatments, absent informed consent.