CompletedNot Applicable

Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker

United States1,361 participantsStarted 2012-05

Plain-language summary

Lung cancer is the number one cancer killer in the USA. Early stage lung cancer is asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and already have advanced stage disease. Low dose CT screening (LDCT) for high risk individuals has recently been shown to decrease lung cancer mortality by 20%. However, 4 out of 5 lung cancer deaths are not prevented with LDCT screening alone.

Who can participate

Age range

50 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Smokers or former smokers * At least 20 pack year history of smoking * Ages 50 - 75 Exclusion Criteria: * Had a CT scan of chest within last 24 months * History of any cancer within 10 yrs (except skin cancer or cervical cancer) * A serious illness that decreases life expectancy to less than 5 years * Any current use of Oxygen * Uncontrolled congestive heart failure or cardiac arrhythmia that would prevent surgery for a lung lesion * Severe COPD or dyspnea that would prevent lung surgery or stereotactic body radiotherapy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

CT alone vs. both Early CDT-Lung test and CT scan.

Timeframe: One year

Trial details

NCT IDNCT01700257

SponsorNational Jewish Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-07

View on ClinicalTrials.gov More High Risk of Developing Lung Cancer trials