Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions

Inclusion Criteria: * Consecutive adult patients who require endoscopic ultrasound and tissue sampling of either a) pancreatic solid lesion, b) subepithelial solid lesion of the esophagus, stomach, duodenum or rectum, c) liver lesion, or d) lymph nodes or mass lesion located adjacent to the esophagus, stomach, duodenum or rectum * Ability to give consent Exclusion Criteria: * Inability to obtain informed consent * Pregnant patients * Patients under the age of 18 * Severe cardiopulmonary disease preventing a safe EUS procedure * Patients unable to safely stop anti-coagulation therapy prior to EUS procedure