Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy

Inclusion Criteria: * Gender: Female * Minimum Age: 18 Years * Maximum Age: 80 Years * indication for elective cholecystectomy on account of symptomatic cholecystolithiasis * age \>=18 years and \<=80 years * legal competence Exclusion Criteria: * Acute cholecystitis or locally complicated disease (gallbladder empyema, choledocholithiasis, pancreatitis, etc.) * liver cirrhosis (Child Pugh A, B, C) * severe comorbidity, class IV or V as defined by the American Society for Anesthesiologists (ASA) * intact hymen * acute vaginal infection * lacking visibility of the uterine orifice * endometriosis * malignoma * obesity with a Body Mass Index (BMI) \> 40 kg/m2 * chronic abuse of analgesics or alcohol * neuromuscular disease that could interfere treatment or measures of pain * history of major abdominal surgery with a high risk of intraperitoneal adhesions (minor operations such as an appendectomy, inguinal hernia repair, minor gynaecological surgery, etc. will not be considered exclusion criteria) * gravidity or breastfeeding * allergy against analgesics * patients who are dependent on or employed by the trial sponsor or physicians * institutionalisation for legal reasons * participation in other clinical studies that could interfere with the present trial * no written informed consent signed