TerminatedPhase 3

Corneal Cross Linking and Topography Guided Excimer Laser Treatment

Austria30 participantsStarted 2010-01

Plain-language summary

Topography guided laser treatment enables the surgeon to correct higher order aberrations in corneas with irregular astigmatism. Several case reports and small uncontrolled trials have been published on the combination of this treatment with corneal cross linking (CCL) in patients with ectatic corneal diseases. This randomized study will evaluate the safety and efficacy of a combined treatment of corneal cross linking with a partial topography guided excimer laser treatment in eyes with progressive ectatic corneal diseases.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Signed informed consent * Patient age 18 - 40 years * Documented progressive corneal ectatic disease except post LASIK/LASEK ectasia Exclusion Criteria: * Allergy to one of the used substances * Tendency towards excessive scar formation * Pregnancy * Rheumatic diseases * Central corneal thickness below 450 µm * Active infection of the study eye * Previous corneal surgery of the study eye

What they're measuring

Safety (Pachymetry, K-readings)

Timeframe: 1 year

uncorrected visual acuity (UVCA)

Timeframe: 1 year

best corrected visual acuity (BCVA)

Timeframe: 1 year

Trial details

NCT IDNCT01682993

SponsorMedical University of Vienna

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-12

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