CompletedNot Applicable

Comparison of Laminaria and Misoprostol for Cervical Preparation Before Second Trimester Surgical Abortion

Israel84 participantsStarted 2007-11

Plain-language summary

This study compares the effectiveness of cervical preparation before second trimester abortion using laminaria versus vaginal Misoprostol. The investigators hypothesize that medical preparation of the cervix with vaginal Misoprostol is superior to mechanical preparation using laminaria. The investigators believe that medical preparation makes the procedure easier to perform, equally safe, without addition of pain or discomfort.

Who can participate

Age range15 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant patients with a viable singleton * Pregnancy 14-20 weeks of gestation * Admitted for termination of pregnancy Exclusion Criteria: * Contraindication for administration of Misoprostol * Patients with more than one previous cesarean section scar * Patients with impaired coagulation * Significant pulmonary or cardiac disease * Non viable pregnancy * Placenta accreta or previa by ultrasound

What they're measuring

Initial cervical opening and the need for further dilatation at the start of the procedure

Timeframe: 8-12 hours after insersion of laminaria or Misoprostol

Trial details

NCT IDNCT01678703

SponsorWolfson Medical Center

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2010-06

View on ClinicalTrials.gov More Induced; Abortion, Nonmedical trials