UnknownNot Applicable

Establishing a Diagnostic Test for Non-tuberculous Mycobacteria Lung Infection Using Non-tuberculous Mycobacteria Antigen Stimulation Test: From Immune Base, Standardized Setup to Validation

Taiwan200 participantsStarted 2011-01

Plain-language summary

1. To compare TLR-2 expression of peripheral blood mononuclear cells and serum downstream cytokines in those with MAC or MAB pulmonary infection and those with MAC or MAB pulmonary colonization and controls. 2. To investigate the response of TLR-2 expression and cytokines activation to NTM stimulation test in patients with MAC or MAB pulmonary infection and colonization and controls. 3. To validate the NTM stimulation test for NTM pulmonary infection.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * A patient has at least 3 sets of respiratory specimen for mycobacterial culture. Exclusion Criteria: * Age younger than 18 years. * Patients who have pregnancy. * Patients who have acquired immunodeficiency syndrome * Patients who have bleeding tendency which can not tolerate venous puncture such as hemophilia, thrombocytopenia. * In NTM infection group, patients having received anti-NTM treatment for one week will be excluded.

What they're measuring

Patients with non-tuberculous pulmonary infection

Timeframe: 3 year

Trial details

NCT IDNCT01676142

SponsorNational Taiwan University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-01

Contact for this trial

Chin-Chung Shu, MD

886972653087 chinchungshu@ntu.edu.tw

View on ClinicalTrials.gov More To Set up NTM Stimulation Test Foar Diagnosing NTM Pulmonary Infectionon. trials