Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy

Inclusion Criteria: * Patient being treated at St. Jude Children's Research Hospital * Permission from participant's physician * Participants must be between the ages of 6 and 30 years of age * Patient is newly diagnosed with LE malignancy as shown by biopsy. Diagnoses include: osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, synovial sarcoma, malignant peripheral nerve sheath sarcoma, malignant fibrous histiocytoma of the bone and chondrosarcoma of the bone, or any other LE malignancy that requires surgical intervention. * Patient has Karnofsky score ≥ 50 or WHO/ECOG ≤ 2 if ≥ 16 years of age * Lansky score ≥ 50 for patients age \< 16 * Surgical intervention is planned primary mechanism of local control * Negative pregnancy test * All patients and/or their parents or legal guardians must sign a written informed consent Exclusion Criteria: * Patients with serious, non-healing wound, ulcer or bone fracture (other than pathologic fracture) * Pre-morbid condition that prevents patient from ambulating * Patients who do not have at least 10 weeks before receiving local control