Oxytocin Antagonist in Patients With Repeated Failure of Implantation (NCT01673399) | Clinical Trial Compass
CompletedPhase 4
Oxytocin Antagonist in Patients With Repeated Failure of Implantation
Belgium138 participantsStarted 2012-02
Plain-language summary
In this study the investigators compare the usual way of embryo transfer (without medication) with an embryo transfer while administering oxytocine antagonist. This to improve implantation and increase the pregnancy rate.
Who can participate
Age range
18 Years – 38 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* IVF/ ICSI patients below 38 years
* 2e to 6e IVF-cycle
Exclusion Criteria:
* patients with endocrinological diseases or problems
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested an oxytocin antagonist specifically for repeated implantation failure — how does blocking oxytocin during embryo transfer actually work to improve implantation, and is there evidence it could help in my specific situation?
2Since this is a Phase 4 trial that has already completed, has my doctor seen the published results, and what did they show about whether the implantation rate actually improved with the oxytocin antagonist compared to not using it?
3Given that this trial focused on patients who had repeated implantation failures, how many failed transfers would I typically need to have before my doctor would consider this kind of approach worth trying?
4Are there any known risks or side effects associated with using an oxytocin antagonist around the time of embryo transfer that I should weigh against the potential benefit?
5Before trying something like an oxytocin antagonist, are there other standard interventions my doctor would recommend investigating first to explain or address my implantation failures?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.