Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.

Inclusion Criteria: * Agree to participate, sign and date ICF; * 18 years old or older; * Mothers who are Rh-negative, negative indirect Coombs analyzed by gel agglutination method, whose just deliveries Rh positive baby. Exclusion Criteria: * Be participating simultaneously or have participated in another clinical trial within the last 12 months; * Mothers who are allergic to any components of the formula; * Mothers who have a history of IgA deficiency or IgA antibody present; * Mothers who have a history of autoimmune hemolytic anemia with hemolysis or with pre-existing risk of hemolysis; * Mothers who have indirect Coombs test positive at the beginning of the treatment; * Rh-negative mothers whose delivered Rh-negative babies; * Abnormalities of the coagulation system; * Patients who made use of vaccines made with live pathogens in the last 03 months or will make during the study; * Patients with clinical diagnosis of prenatal liver and / or severe nephropathy; * Principal Investigator of the study criteria.