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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria :
* Age ≥ 18 years,
* Fœtal Infection with CMV authenticated by the positivity of the research of the viral genome by PCR in the amniotic liquid,
* Echographic Assessment revealing at least one cerebral extra anomaly being able to be in connection with the infection with CMV,
* And/or one isolated cerebral anomaly :
* Ventriculomégalie measured with the ventricular crossroads \< 15mm
* Signs of lenticulo-striated vasculopathy
* Intraparenchymateuses calcifications
* Intra-ventricular adherences
* And/or biological signs of generilazed infection to CMV :
* fetal viremia \> 3000 copies/ml
* platelet \< 100 000/cc
* Absence of request for termination of pregnancy from the start,
* Acceptance of a strict follow-up by a Multi-field Center of Prenatal diagnosis and of an optimal observance of the founded treatment,
* Collection of the written assent to take part in the test.
* Affiliation with a mode of social security or equivalent.
Exclusion criteria :
* Not affiliation with a mode of social security (profit or having right)
* Patient of less than 18 years,
* Patient presenting another pathology obstetrical or medical (in particular hepatic or renal) preexistent to tracking or contra-indicating the use of valacyclovir,
* Patientes whose fœtus does not present any echographic sign being able to be in connection with the infection with CMV,
* Patientes whose fœtus presents at least one cerebral echographic anomaly :
Ventriculomégalie measured wi…