Comparison of the Bilateral TAP Block Versus Curare in Muscle Relaxation of the Abdominal Wall Du… (NCT01628952) | Clinical Trial Compass
CompletedPhase 4
Comparison of the Bilateral TAP Block Versus Curare in Muscle Relaxation of the Abdominal Wall During Laparoscopic Digestive Surgery: Prospective Randomized Study
France60 participantsStarted 2012-06
Plain-language summary
This is a Biomedical Research, prospective, randomized, controlled single-blind mono centric, phase IV comparison trial of the bilateral TAP block versus curare in muscle relaxation of the abdominal wall during laparoscopic digestive surgery.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion Criteria:
* Patients older than 18 years and under 75 years
* Informed consent signed
* ASA I, II and III
* Patient affiliated to social security
Exclusion Criteria:
* ASA IV
* BMI\> 35 kg / m
* Personal or family history of malignant hyperthermia
* History of allergy or hypersensitivity to intravenous anesthetics (remifentanil), local anesthetics or muscle relaxants
* Contraindications to sevoflurane: a history of malignant hyperthermia, history of liver disease after sevoflurane anesthesia, halogenated agents or hypersensitivity to any of these components.
* Contraindications to succinylcholine: hyperkalemia, plasma cholinesterase deficiency nickname, para or tetraplegia more than 24 hours, burns over 24
* Contraindications to cisatracurium: myasthenia
* Neuromuscular diseases
* Contraindications to local anesthetics: hypersensitivity to local anesthetics of the amide, intravenous regional anesthesia, porphyria, ventricular atrial conduction disturbances, epilepsy uncontrolled by treatment
* Pregnancy and lactation
* severe coagulation disorders
* Inability to understand and give informed consent
* Patient under guardianship, curatorship or protected
* Indication of use of a hypnotic ketamine (BIS change)