Second Look Laparoscopy in Colorectal Cancer

Inclusion Criteria: * Histologic diagnosis colorectal adenocarcinoma * Mucinous histotype * Stage I-III * Radical (R0) surgical resection of primary tumor * CT scan with contrast showing no evidence of disease recurrence 6 months after primary surgery * Age ≥ 18 ≤ 65 years * Performance Status ECOG ≤1 * Normal hepatic, renal and hematologic function * Adjuvant chemotherapy permitted * Signed informed consent Exclusion Criteria: * Residual disease after surgical resection of primary tumor * Distant metastasis * Active systemic infection * Chronic cardiovascular illness that would contraindicate abdominal dilatation with pneumoperitoneum * Concomitant or previous malignancy with 5 years of surgical resection of primary tumor (except for adequately treated non-melanoma skin cancer and in situ cervical cancer) * Pregnancy or lactation * Refusal or incapability of providing informed consent * Impossibility of complying with study schedules and follow-up