UnknownNot Applicable

Continuous Regional Arterial Infusion of Low Molecular Weight Heparin in Patients With Severe Acute Pancreatitis

China60 participantsStarted 2011-09

Plain-language summary

Our animal studies found that continuous regional arterial infusion (CRAI in the celiac trunk) of low molecular weight heparin (LMWH) could alleviate inflammation, improve global hemodynamics and restore organ function in a porcine model of severe acute pancreatitis (SAP,unpublished). In this study, the investigators aim to evaluate the effects of CRAI of LMWH in the treatment of SAP patients. The investigators suppose CRAI could help improve the outcomes of these patients.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Symptoms and signs of severe acute pancreatitis according to Atlanta criteria * Within 3 days from the onset of the disease * Available for interventional treatment(not sensible to radiocontrast agent) Exclusion Criteria: * Pregnant pancreatitis * Receiving surgery or aspiration before;need of early surgery * Patients with coagulation disorders

What they're measuring

coagulation related complications

Timeframe: 14 days after the placement of celiac trunk catheter

Pancreatic infection

Timeframe: 28 days

Trial details

NCT IDNCT01626911

SponsorNanjing University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-12

Contact for this trial

Weiqin Li, Dr

+86-025-80860066 kkb9832@gmail.com

View on ClinicalTrials.gov More Acute Pancreatitis trials