CompletedNot Applicable

Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery

South Korea61 participantsStarted 2012-06

Plain-language summary

There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD. However, there have been no evidence of which degree of partial neuromuscular blockade should be performed during LSR monitoring under sevoflurane anesthesia. Therefore, the investigators performed a randomized controlled trial to evaluate the effect of different degree of partial neuromuscular blockade on the LSR monitoring for MVD surgery.

Who can participate

Age range20 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Those who undergo microvascular decompression with sevoflurane anesthesia by diagnosis of hemifacial spasm in our institution Exclusion Criteria: * Patients were excluded from the study if they had any of following: severe cardiopulmonary disorder with hemodynamic unstability (pulmonary hypertension, cardiomyopathy, mechanical ventilation, American Society of Anesthesiologists physical status III or more), severe hepatic or renal disease. * Those who can not undergo MEP monitoring due to central or peripheral neuromuscular disease, e.g. cerebral palsy, myasthenia gravis, acute spinal injury, neurologic shock

What they're measuring

Lateral spread response

Timeframe: baseline (30 min after anesthetic induction)

Lateral spread response

Timeframe: before dura opening (45 minute after anesthetic induction)

Lateral spread response

Timeframe: after dura opening (60 min after anesthetic induction)

Lateral spread response

Timeframe: before facial nerve decompression (90 minutes after anesthetic induction)

Lateral spread response

Timeframe: after facial nerve decompression (120 min after anesthetic induction)

Lateral spread response

Timeframe: after dura closure (150 min after anesthetic induction)

Trial details

NCT IDNCT01613781

SponsorSamsung Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-02

View on ClinicalTrials.gov More Hemifacial Spasm trials

Plain-language summary

Who can participate

Age range20 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Lateral spread response

Timeframe: baseline (30 min after anesthetic induction)

Lateral spread response

Timeframe: before dura opening (45 minute after anesthetic induction)

Lateral spread response

Timeframe: after dura opening (60 min after anesthetic induction)

Lateral spread response

Timeframe: before facial nerve decompression (90 minutes after anesthetic induction)

Lateral spread response

Timeframe: after facial nerve decompression (120 min after anesthetic induction)

Lateral spread response

Timeframe: after dura closure (150 min after anesthetic induction)