Spectral Domain Optical Coherence Tomography Analysis for Glaucoma
Turkey (Türkiye)169 participantsStarted 2010-11
Plain-language summary
The aim of this study is to examine whether there is a difference in macular ganglion cell complex thickness and retinal nerve fiber layer thickness in early-stage Primary open angle glaucoma and normal tension glaucoma with spectral domain OCT.
Who can participate
Age range28 Years – 72 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
The POAG group inclusion criteria were;
* IOP higher than 21 mmHg before treatment on three different visits,
* Best corrected VA of 20/25 or better with a spherical equivalent within ±5 D and a cylinder correction within +3 D;
* An open angle confirmed by gonioscopy.
* Glaucomatous optic disc damage defined as by the presence of glaucomatous optic neuropathy like rim thinning (diffuse or local), cupping, notching, and a cup/disc ratio \>0.2 with asymmetry.
NTG group were included if;
• They had the same optic disc and visual field criteria as for the POAG patients with the exception that their IOP was as ≤21 mmHg on three separate visits without any glaucomatous treatment.
The control group
* Who had no ocular disease
* Who had not undergone ocular surgery or laser procedures.
* With a normal anterior segment, open angles, and normal posterior segment findings also normal optic nerve head appearance in their ophthalmic examination.
* The IOP measurements were lower than 21 mmHg, and full-threshold 30-2 HFA were also within normal limits in the control group.
Exclusion Criteria:
* Subjects with any retinal disease, diabetes mellitus, or neurological disease or who had undergone ocular surgery and laser procedures.
* Subjects with pseudoexfoliation glaucoma and pigmentary glaucoma were excluded.
What they're measuring
1
Ganglion cell complex, retinal nerve fiber layer and retinal thickness measurements of glaucoma patients using spectral domain OCT.