CompletedNot Applicable

Maternal Plasmatic Regulatory T Cells and Th17 as Possible Diagnosis Markers of Acute Chorioamnionitis

France95 participantsStarted 2013-03-26

Plain-language summary

The purpose of this study is to evaluate if regulator T cells (Treg) and Th17 level modifications in maternal blood and placenta could be correlated to a chorioamnionitis, in women hospitalized for PPROM.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Informed consent signed * Patient affiliated with a social security scheme * term pregnancy betwwen 24 and 34 weeks * PPROM diagnosis * singleton pregnancy Exclusion Criteria: * delivery occured in 1 hour after admission * hemorragic praevia placenta or retro-placental hematoma * confirmed autoimmune or inflammatory disease * confirmed infectious disease by VIH, VHC, and VHB

What they're measuring

Evaluate the percentage of Treg in maternal blood at the time of admission

Timeframe: the day of delivery or 7 days after the admission if no delivery

Trial details

NCT IDNCT01610258

SponsorCentre Hospitalier Universitaire Dijon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-12-08

View on ClinicalTrials.gov More Pathology of Pregnancy trials