TerminatedPhase 4

Gene Expression Profile After Gonadotropin Releasing Hormone (GnRH) Agonist Trigger of Oocyte Maturation

Stopped: Difficult to recruit patients

United States7 participantsStarted 2012-04

Plain-language summary

The purpose of this study is to compare gene expression profiles in endometrial biopsies during the window of implantation after triggers of oocyte maturation using GnRH agonist or hCG and compared with their natural cycles in order to identify genes that may be dysregulated in GnRH agonist-triggered cycles. The investigators also intend to evaluate patients feeling of well being and physical quality of life after GnRH agonist trigger compared with hCG trigger.

Who can participate

Age range21 Years – 33 Years

SexFEMALE

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Inclusion Criteria: * Oocyte donors * Ages between 21 and 33 * Normal baseline serum FSH \< 10mIU/mL Exclusion Criteria: * Hypothalamic dysfunction * Smokers * Baseline serum FSH ≥ 10mIU/mL

What they're measuring

Endometrial Gene Expression Profile

Timeframe: 7 days after trigger of oocyte maturation

Trial details

NCT IDNCT01606709

SponsorUConn Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

Results submitted2017-04-17

View on ClinicalTrials.gov More Endometrial Receptivity trials