Description of Abdominal and Gluteo-femoral Subcutaneous Adipose Tissue Cell Population in Women … (NCT01605578) | Clinical Trial Compass
CompletedNot Applicable
Description of Abdominal and Gluteo-femoral Subcutaneous Adipose Tissue Cell Population in Women - GLUTAB
France20 participantsStarted 2012-05-14
Plain-language summary
The purpose of this study is to compare, in healthy women, the adipose tissue composition between abdomen and thigh and then determine whether differences exist independently of the state of obesity.
The findings of this study may help to explain the mechanism contributing to a beneficial role of gluteo-femoral fat contrasting with a deleterious role of abdominal fat on cardiovascular and metabolic dysfunctions.
Who can participate
Age range
25 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* women between 15 and 45 years old
* with genital activity
* stable weight during the previous 3 months
* BMI from 20 to 28
* regular menstrual cycles (28 +/- 2 days) during the previous 3 months
* reliable means of contraception (systemic hormonal contraception, intrauterine contraceptive device, tubal ligation)
* using the same way of contraception during the previous 3 months
* normal clinical examination
* able to be compliant with the schedule of protocol assessments
* willing and able to provide written informed consent
* affiliated to a National Health Service
* agreeing to being registered on the national file for subjects participating in biomedical research
Exclusion Criteria:
* Exclusions related to significant medical disturbances :
* type I and II diabetes
* early menopause
* serious psychological disorders
* uncontrolled thyroid disorders
* know allergy to local anesthetics especially Xylocaine
* abnormal laboratory results
* medical history that, in the opinion of the investigator, makes the subject unsuitable for enrollment
* positive test result for HIV, HCV and/or HBV virus
* positive pregnancy test
* Exclusions related to subject lifestyle :
* smoking \> 10 cigarettes per day
* smoking cessation during the previous 3 months
* weight fluctuation (\>3kg) during the previous 3 months
* alcohol abuse
* coffee or tea consumption \> 6 cups per day
* high consumption of drinks comprising xanthine bases (\>0.5 liters/day)
* consumption of dr…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To compare the number and the phenotype of cells between abdominal and gluteo-femoral adipose tissue in women.
Timeframe: There is no time frame. It's a comparison of adipose tissue composition between two locations, collected both at visit 2 (inclusion).
Trial details
NCT IDNCT01605578
SponsorInstitut National de la Santé Et de la Recherche Médicale, France