GP VS TP in the Treatment of Advanced Nasopharyngeal Carcinoma in Northwest China

Inclusion Criteria: * Histologically proven WHO II\~III native NPC in northwest region of China; * 18 Years to 70 Years; * stages III-IVb according to AJCC stage classification(7th edition), no previous chemotherapy and radiotherapy; * Performance status: 0-1(ECOG); * WBC \> 4.0X109/L, PLT \> 100X109/L, with normal hepatic function(AST, ALT \< 2.5 x upper limit of normal, and bilirubin \< 1.5 x upper limit of normal), with normal renal function (Creatinine \< 1.5 x upper limit of normal); * Ability to comply with trial requirements. Exclusion Criteria: * Evidence of metastases by clinical or radiographic examinations; * History of malignancy; * Prior chemotherapy or anticancer biologic therapy for any type of cancer, or prior radiotherapy to the head and neck region except for radioactive iodine therapy.; * Patients with uncontrolled intercurrent disease; * Patients with currently active malignancy; * Pregnant or lactating women patients of childbearing potential who are unwilling to practice adequate contraception during study treatment and for two months after the last administration of study drug.