Vascular Subphenotypes of Lung Disease in HIV & COPD (NCT01581086) | Clinical Trial Compass
CompletedNot Applicable
Vascular Subphenotypes of Lung Disease in HIV & COPD
United States30 participantsStarted 2012-01
Plain-language summary
This study is looking for high blood pressure in the lungs (Pulmonary artery hypertension PAH) in HIV and COPD patients.
Who can participate
Age range18 Years – 80 Years
SexALL
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Inclusion Criteria:
* Male/Female 18-80 years of age.
* Subject has been previously enrolled in PACT/MAC/ECRC study.
* Must have recent ProBNP test \>120pg/ml or abnormal echocardiogram (right ventricular systolic pressure \>or=40mmHg) without evidence of left sided heart failure.
Exclusion Criteria:
* Previous diagnosis of congenital heart failure.
* If evidence of Left ventricular systolic or diastolic dysfunction, echo will be reviewed by the PI on a case by case basis.
* Creatine clearance \<60ml/min per 1.73 m2.
* Undiagnosed chest pain or myocardial infarction, stroke or cardiovascular event within 3 months.
* Pregnancy.
* Subjects receiving chronic anticoagulant.
* Inability to complete the 6 minute walk test.