Narrow Band Imaging Project on Barrett's Esophagus

Inclusion Criteria: * Patients age: ≥ 18 years * Undergoing endoscopy for surveillance or endoscopic treatment of Barrett's esophagus * Ability to take oral proton pump inhibitor * For female subjects of childbearing potential, a negative urine pregnancy test within 2 weeks of enrollment and any subsequent endoscopy encounter * Subject is eligible for treatment and follow-up endoscopy and biopsy as required by the investigational plan * Ability to discontinue Aspirin/NSAIDs/Clopidogrel 7 days before and after all ablation procedures * Ability to provide written, informed consent and understands the responsibilities of trial participation Exclusion Criteria: * The subject is pregnant or planning a pregnancy during the study period (12 months after treatment) * Esophageal stricture preventing passage of endoscope or catheter * Active erosive esophagitis * Prior endoscopic therapy with endoscopic mucosal resection, radiofrequency ablation, etc. * History of esophageal varices or coagulopathy * Prior radiation therapy to the esophagus, except head and neck region radiation therapy. * Evidence of esophageal varices during treatment endoscopy * Subject has a known history of unresolved drug or alcohol dependency that would limit ability to comprehend or follow instructions related to informed consent, post-treatment instructions, or follow-up guidelines * The subject is currently enrolled in an investigational drug or device trial that clinically interferes with the current stud…