UnknownNot Applicable

Treatment of Xerostomia by Herbal Preparation

South Korea96 participantsStarted 2012-04

Plain-language summary

The aims of this study are to investigate the effect of famous herbal formula extract on xerostomia, and to determine whether this formula affect various xerostomia-related questionnaires, salivary flow rate, residual saliva and salivary tests.

Who can participate

Age range60 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age of 60 - 80
✓. The visual analog scale for xerostomia must represent more than 4 points during 2wks prior to enrollment
✓. One who has less than 0.3 ml/min of unstimulated salivary flow rate
✓. One who has complained of xerostomia for at least 3months
✓. One who is able to read, write, hear, see something
✓. One who agree on not taking other therapies during experimental period
✓. One who agree on consent form

Exclusion criteria

✕. One who is taking the treatment for autoimmune disease such as sjogren's disease, rheumatic disease, systemic lupus erythematosus etc
✕. One who has the history of taking radiotherapy on head and neck or history of organ transplantation
✕. One who has severe mental illness such as depression
✕. One who takes oriental medicine or health functional food within 2 wks before enrollment
✕. One who takes the remedies on the purpose of relieving xerostomia such as pilocarpine, cevimeline, gargle solution, frequent gum use, intra oral devices and toothpaste etc.

What they're measuring

Visual Analogue Scale (VAS) for xerostomia

Timeframe: Visit 1(0week), Visit 2(4week), Visit 3(8week), Visit 4(10week)

Trial details

NCT IDNCT01579877

SponsorKorea Health Industry Development Institute

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2013-09

Contact for this trial

Jinsung Kim, doctorate

+82-2-958-8895 oridoc@khu.ac.kr

View on ClinicalTrials.gov More Xerostomia trials