Evaluation of the Use of Indomethacin as Co-treatment in Women With Preterm Labor and High Risk of Intraamniotic Inflammation

Inclusion Criteria: * pregnant women with preterm labor admitted to hospital and treated with tocolysis * pregnant women less than 28.0 and those women from 28.0 to 32.0 with a sonographic cervical length \< 15 mm * single pregnancy * normal amniotic fluid * normal arterial ductus Exclusion Criteria: * Age below 18 years * previous use of indomethacin in the index pregnancy * chorioamnionitis, preterm prelabour rupture of membranes or those fetal or maternal pathologies which could be responsible of an iatrogenic preterm delivery. * oligohydramnios * allergy to NSAID * previous history of gastrointestinal bleeding * use of NSAID contraindicated * not adherence to the study