CompletedNot Applicable

Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors

50 participantsStarted 2012-04

Plain-language summary

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer. PURPOSE: This research trial is studying genes in tumor samples from younger patients with ovarian or testicular sex cord stromal tumors.

Who can participate

Age range120 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Fixed and frozen tissue samples from the ATBR01 B1 tissue bank and from the International Pleuropulmonary Blastoma Registry, Children's Hospital of Boston, and Massachusetts General Hospital * Tissue samples from patients diagnosed with: * Ovarian * Sertoli-Leydig cell tumor * Juvenile granulosa cell tumor * Adult granulosa cell tumor * Gynandroblastoma * Sex cord stromal tumor with annular tubules * Sex cord stromal tumor, undifferentiated * Sertoli tumor * Leydig tumor * Testicular: * Granulosa cell tumor * Sertoli tumor * Leydig tumor * Sertoli-Leydig * Undifferentiated stromal tumor PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

Correlation between DICER1 mutations and miRNA pathways with outcomes using descriptive analysis

Trial details

NCT IDNCT01572467

SponsorChildren's Oncology Group

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2016-07

View on ClinicalTrials.gov More Childhood Germ Cell Tumor trials