Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healt… (NCT01570426) | Clinical Trial Compass
UnknownNot Applicable
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
United States240 participantsStarted 2007-07
Plain-language summary
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from children without these problems. The investigators want to understand how these 4 groups of children differ in brain activity, function, and structure.
Who can participate
Age range7 Years – 17 Years
SexALL
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General Inclusion Criteria:
* English- speaking,children \& adolescents between the ages of 7- 17
* consenting parent/guardian
General Exclusion Criteria:
* estimated IQ less than 70
* substance/alcohol use or dependence within the last 2 months
* Autism Spectrum Disorders or primary psychosis
* medical/neurological conditions that mimic the psychiatric disorders of interest
* implanted metal (NO BRACES or COCHLEAR IMPLANT)
For inclusion in the Bipolar group, participants:
* have to meet Diagnostic and Statistical Manual, 4th Edition Text Revision (DSM-IV-TR) criteria for BD Type I, including at least one lifetime episode of mania
For inclusion in the ADHD/ADD group, participants:
* meet DSM-IV-TR criteria for any subtype of ADHD or ADD
* can not currently meet diagnostic criteria for bipolar, depressive or anxiety disorders
For inclusion in the Generalized Anxiety Group (GAD), participants:
* have to meet DSM-IV-TR criteria for GAD
* can not currently meet diagnostic criteria for Obsessive Compulsive Disorder (OCD) or Post-Traumatic Stress Disorder (PTSD)
For inclusion in the Healthy Control group, participants:
* can not have a past/current history of psychiatric or substance use disorders
* can not have a first-degree relative (parents, brothers/sisters) with a history of psychiatric illness
What they're measuring
1
Behavioral performance on computerized tasks
Timeframe: Day 1
2
MRI data (neural activation) during behavioral task