Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors

Inclusion Criteria: * Patients diagnosed with acromegaly or a nonfunctioning pituitary who will receive treatment for the pituitary condition. * Study subjects must agree to participate in this study and provide written consent. * Site- Emory Clinic/Emory University hospital. * Stage of Disease: Patients with active acromegaly that is either newly diagnosed or uncontrolled on current therapy (as shown by GH/IGF-1 levels). Patients with nonfunctioning pituitary adenoma in whom surgical intervention planned based on current guidelines will serve as a control group. * Age: Study subjects must be over 18 years of age. Exclusion Criteria: * Age \< 18 years old * Prior other diseases: Patients chronic renal disease stage 3 or worse (estimated GFR \> 60).