CompletedNot Applicable

Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas

United States70 participantsStarted 2016-05

Plain-language summary

This research trial studies genes in tissue samples from younger and adolescent patients with soft tissue sarcomas. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer

Who can participate

Age range30 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Archived non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) tumor-derived DNA * Synovial sarcoma, malignant peripheral nerve sheath tumor (MPNST), soft tissue sarcoma not otherwise specified (NOS), or other less common pediatric NRSTS * Formalin-fixed, paraffin-embedded (FFPE) tissue from patients enrolled on: * COG-D9902 Soft Tissue Sarcoma (STS) Biology and Banking Protocol * COG-ARST0332 A Risk-Based Treatment for Pediatric NRSTS Study * See Disease Characteristics

What they're measuring

Frequency of individual mutated genes in patients with NRSTS

Timeframe: Up to 1 month

Genetic changes that are most common and likely to have the greatest therapeutic impact

Timeframe: Up to 1 month

Trial details

NCT IDNCT01567046

SponsorChildren's Oncology Group

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2016-05

View on ClinicalTrials.gov More Childhood Alveolar Soft-part Sarcoma trials