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Research of the Key Technology and Standardization of Minimal Invasive Treatment for Hepatolithiasis

China100 participantsStarted 2012-01

Plain-language summary

The purpose of this research is to investigate the key technology and the related issues of minimal invasive treatment for hepatolithiasis and to build new methods of minimal invasive operation for hepatolithiasis. The validity, feasibility and limitations of the laparoscopic operation were assessed objectively through our clinical prospective study. The technique points, indications and contraindications were summarized to evaluate the status and role of minimal invasive laparoscopic operation in the treatment of hepatolithiasis.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients with regional stones distributed in a segment, lobe or half liver, combined or not combined with extrahepatic biliary calculi, hepatic parenchymal atrophy or fibrosis in the lesion region
✓. Liver function \> Child-pugh level B, no severe biliary cirrhosis, ICG ≤ 15%, the residual liver volume and standard liver volume ratio ≥ 40%
✓. Patients with good general condition, the conditions of open Anatomical Hepatectomy were achieved

Exclusion criteria

✕. Written informed consent
✕. Age: older than 70 years old, younger than 18 years old
✕. Patients with bad general condition or important organ lesions, liver resection could not be tolerated
✕. Complicated case needed to get emergency operation
✕. Combined with severe liver atrophy hypertrophy syndrome, hepatic portal transposition or hilar biliary fibrosis / stenosis
✕. Combined with severe biliary cirrhosis and portal hypertension, severe varicose of hepatic portal vein , hepatic insufficiency
✕. Diagnosed with cholangiocellular carcinoma intraoperatively or by postoperative pathology
✕. Contraindication of laparoscopy: Combined with complicated acute cholangitis, repeated biliary tract operation, heavy intra-abdominal adhesion, Trocar can not be placed in. Artificial pneumoperitoneum could not be tolerated

What they're measuring

Number of participants with residual stones or cholangitis symptoms

Timeframe: up to 5 years postoperation

Trial details

NCT IDNCT01563510

SponsorShuguo Zheng, MD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12

View on ClinicalTrials.gov More Biliary Stones trials