RecruitingNot Applicable

Cryopreservation of Ovarian Tissue

United States300 participantsStarted 1997-04

Plain-language summary

The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.

Who can participate

Age range

45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Females 0-45 years of age who are premenopausal * Treatment plan that will likely result in premature menopause or premature ovarian failure * This includes patients receiving: * Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy * Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients * Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos. * Previous treatment for cancer is acceptable if patient still has ovarian function * Patient is medically stable enough to undergo surgery (cleared for anesthesia) Exclusion Criteria: * Patients not meeting the above criteria * Patients who have not received medical clearance from their physicians to undergo surgery * Patients already experiencing menopause.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

CRYOPRESERVATION OF OVARIAN TISSUE FOR POTENTIAL IN VITRO MATURATION OR AUTOLOGOUS TRANSPLANTATION

Timeframe: 6 months to a year post surgery, hormone testing will be performed to test ovarian function.

Trial details

NCT IDNCT01558544

SponsorWeill Medical College of Cornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-10-31

Contact for this trial

Rodriq E. Stubbs, NP

646-962-3276 res2011@med.cornell.edu

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