CompletedPhase 2

Tramadol Versus Lidocaine Infiltration for Tonsillectomy

Saudi Arabia90 participantsStarted 2011-12

Plain-language summary

The investigators postulate that the use of pre-incisional peritonsillar infiltration of tramadol or lidocaine reduces both the inflammatory response and postoperative analgesic consumption, without harmful effects. Therefore, the present study is designed to evaluate the effects of infiltration of tramadol or lidocaine on the postoperative acute-phase serum protein, C-reactive protein, and analgesic consumption after tonsillectomy.

Who can participate

Age range2 Years – 6 Years

SexALL

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Inclusion Criteria: * ASA I \& II preschool children aged 2-6 years, undergoing elective tonsillectomy with or without adenoidectomy, under general anaesthesia. Indications for tonsillectomy will be chronic recurrent tonsillitis or tonsillar hypertrophy Exclusion Criteria: * Patients with a history of allergy to tramadol or amide local anaesthetics, epilepsy, or taking cardiovascular, antihypertensive, steroids, or anti-inflammatory medications, those with cardiac, liver, or kidney diseases, or any underlying systemic diseases or acute infectious processes will be excluded from the study. All operations will be performed, using an electro-dissection technique, by the same surgeon.

What they're measuring

inflammatory and stress response

Timeframe: 24 hours

Trial details

NCT IDNCT01552096

SponsorImam Abdulrahman Bin Faisal University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-10

View on ClinicalTrials.gov More Peri-tonsillar Analgesic Infiltration trials