Clinical Study on Silk Sericin Wound Dressing for Split-thickness Skin Graft Donor Sites Treatment

Inclusion Criteria: * Aged 18-60 years * Patients who require STSG such as burn, trauma, venous ulcers, or surgical removal of cutaneous malignancies etc. * Patients whom surgeons assess that ready for undergoing STSG * Sufficient normal skin at anterolateral thigh area for 1 or more STSG donor sites * The thickness of donor sites fall between 0.15-0.45 mm (0.006-0.018 inches) and their sizes are at least 100 cm2 * Patients who are willing to participate in the trial and to sign the informed consent form. Exclusion Criteria: * Use others area for STSG donor sites other than thigh * Donor sites are located at high risk of infection such as harvesting closed to current infective wound (excessive purulent discharge or bad odor) * Patients who are immunocompromised or mental defect * Patients who cannot or not willing to comply with the study protocol * Known allergy or hypersensitivity reaction to silk sericin or chlorhexidine acetate * Pregnancy or lactation