Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease

Inclusion Criteria * Diagnosis: diagnostic evidence of probable Alzheimer's disease (AD) consistent with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV-TR) 290.00 or 290.10 * Mini Mental State Examination (MMSE) less than or equal to 12 and greater than or equal to1 inclusive, at Screening * SIB less than or equal to 90 and greater than or equal to10 at both Screening and Baseline * No evidence of focal disease to account for dementia on any cranial image (magnetic resonance imaging \[MRI\] or computed tomography \[CT\]). * Subject age range: male and female subjects greater than or equal to 50 years of age inclusive * Outpatients (patients in nursing homes are eligible) * The subject must have a caregiver who will provide informed consent separately for his/her own participation in the study, who will have regular contact with the subject. * Stable donepezil dose of 10 mg, taken as a single, daily dose for greater than or equal to 3 months prior to the Screening visit * Subjects who can swallow hole tablets, as tablets should not be broken or crushed * Comorbid medical conditions must be clinically stable prior to Screening unless otherwise specified. * Written informed consent will be obtained from the subject (if possible) or from the subject's legal guardian or other representative (according to Japanese regulations as appropriate) prior to beginning screening activities. Exclusion Criteria * Subjects with a known history of disorders tha…