By InvitationEarly Phase 1

Asthma Inflammation Research

United States60 participantsStarted 2011-01

Plain-language summary

The overall goal of the Asthma Inflammation Research \[AIR\] Translational Program is to create an integrated multidisciplinary team for the focused purpose of development of diagnostic and prognostic tests informative for airway inflammation, and for the design of innovative, targeted biologic therapeutics. The overarching aims of the AIR program are to conceptualize, develop, and test the next-generation therapeutics, and novel asthma diagnostic and prognostic tools that will allow us to improve the standard of asthma care.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Asthma diagnosed by a medical specialist and/or history of positive methacholine rest and/or reversibility of \>10% of FEV1 * FEV1 is within acceptable limits * Informed Consent is present Exclusion Criteria: * Diabetes (fasting blood sugar \>110 mg/dL) * Any milk allergies * Coconut allergies * BMI \>40 kg/m2, * Inability to maintain diet intervention * Current smoking or smoking history of greater than 10 pack-years * Any other significant respiratory or cardiac disease or the presence of clinically important comorbidities, including, uncontrolled coronary artery disease, acute or and chronic renal failure

What they're measuring

Maintaining a tolerance to Medium Chain Triglyceride (MCT) additive for Asthmatics

Timeframe: 24 weeks

Trial details

NCT IDNCT01536522

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06

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