TerminatedNot Applicable

Effect of Epinephrine on Systemic Absorption of Mepivacaine in Uremic Patients

Stopped: Slow recruitment

Denmark16 participantsStarted 2012-09

Plain-language summary

The aim of this study is to determine the effect of epinephrine on systemic absorption of local anaesthetic mepivacaine administered for brachial plexus block in uremic patients scheduled for creation or repair of an arteriovenous fistula. Furthermore, an impact of epinephrine on the central circulation and peripheral tissue oxygenation will be evaluated.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient acceptance of regional anaesthesia Exclusion Criteria: * peripheral arteriosclerosis * diabetes mellitus * bleeding disorder * infection at the puncture site * allergy to mepivacaine * pregnancy

What they're measuring

Plasma concentration of mepivacaine

Timeframe: 0, 5, 10, 20, 30, 45, 60, 120, and 180 min after blockade

Trial details

NCT IDNCT01533545

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-09

View on ClinicalTrials.gov More Renal Insufficiency, Chronic trials