CompletedNot Applicable

Safety and Metabolic Study of Highly Active Antiretroviral Therapy (HAART) in Malnourished Children With HIV

Malawi42 participantsStarted 2011-07

Plain-language summary

It is unclear whether children with HIV and severe acute malnutrition can be started on highly active antiretroviral therapy (HAART) safely while they are still malnourished and the manner in which this therapy should start. This study will examine the safety, efficacy, and metabolism of children started on HAART while still severely malnourished.

Who can participate

Age range6 Months – 59 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * HIV-infected about to start on HAART for the first time * 6-59 months old Exclusion Criteria: * also being treated for TB * other chronic illness (e.g., congenital heart disease, cerebral palsy)

What they're measuring

Pharmacokinetics

Timeframe: 6 weeks

Trial details

NCT IDNCT01529125

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-09

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