Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric Glaucoma

Inclusion Criteria: * Children of either sexes, aged 0-12 years * Diagnosis of mono- or bilateral primary congenital glaucoma * IOP greater than or equal to 22 mmHg and lower than 27 mmHg * Only one previous ocular hypotensive surgical procedure for treatment of glaucoma among the following: goniotomy, trabeculotomy, trabeculotomy with adjunct of mitomycin C) (only for medical treatment at least one month before) * Parent informed consent to data processing (at registration) * Parent informed consent before any study procedure Exclusion Criteria: * Secondary glaucoma (Sturge-Weber syndrome, type I neurofibromatosis, retinoblastoma, steroid-induced glaucoma, etc.) * Presence of concomitant abnormalities of the anterior segment of the eye (cataract, iridocorneal dysgenesia, congenital uveal ectropion uvea, etc.) * Previous treatment with the study drugs * Presence of concomitant systemic diseases (asthma, hypertension, cardiac disease, renal failure, etc.) that needs treatment with drugs, that could influence IOP (steroids, beta-blockers, angiotensin-converting-enzyme inhibitor -inhibitors diuretics, etc.) * Abnormalities of the cornea that could influence IOP readings (marked cornea edema)